Overview
SCIENTIFIC SCORE
Questionable
Based on 16 Researches
6.5
USERS' SCORE
Good
Based on 3 Reviews
8.4
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
125 mcg (5,000 IU)
625%
Top Medical Research Studies
1
Vitamin D supplementation ineffective
We explored the direct impact of vitamin D supplementation on erectile dysfunction among older men through the D-Health Trial, which followed nearly 11,530 participants aged 60 to 84. Participants were randomly assigned to receive either 60,000 IU of vitamin D monthly or a placebo over a period of up to five years.
After three years, we assessed erectile dysfunction and found that while vitamin D levels increased significantly in the treatment group, the prevalence of erectile dysfunction remained almost identical between both groups—58.8% in the vitamin D group compared to 59.0% in the placebo group. Importantly, our analyses showed no evidence that vitamin D supplementation made any difference in erectile dysfunction for any subgroup of older men evaluated.
In conclusion, our findings suggest that taking vitamin D supplements is unlikely to prevent or alleviate erectile dysfunction. This highlights the need for further exploration into effective treatments for this common condition among older men.
After three years, we assessed erectile dysfunction and found that while vitamin D levels increased significantly in the treatment group, the prevalence of erectile dysfunction remained almost identical between both groups—58.8% in the vitamin D group compared to 59.0% in the placebo group. Importantly, our analyses showed no evidence that vitamin D supplementation made any difference in erectile dysfunction for any subgroup of older men evaluated.
In conclusion, our findings suggest that taking vitamin D supplements is unlikely to prevent or alleviate erectile dysfunction. This highlights the need for further exploration into effective treatments for this common condition among older men.
Read More
9
We investigated the effects of vitamin D on erectile dysfunction specifically in the context of nerve injury. This research involved 18 male Sprague-Dawley rats, divided into groups for control, nerve injury, and treatment with vitamin D after nerve injury. By measuring changes in intracavernosal pressure, we could assess how well vitamin D helped restore erectile function in the rats with nerve damage.
Our findings revealed that vitamin D not only eased the negative effects of hypoxia and reduced fibrosis but also promoted the restoration of erectile function. We observed that vitamin D improved blood flow in the penis by enhancing the function of certain important proteins while decreasing markers related to tissue damage. Notably, the treatment had a significant impact on the autophagy process—a way cells renew themselves—which is crucial for recovery in this scenario. Furthermore, vitamin D helped reduce apoptosis, or programmed cell death, which can complicate recovery after nerve injury.
Overall, our study indicates that vitamin D can be a vital ally in recovering erectile function following nerve damage, thanks to its ability to promote healing and reduce cell death within the affected tissues.
Our findings revealed that vitamin D not only eased the negative effects of hypoxia and reduced fibrosis but also promoted the restoration of erectile function. We observed that vitamin D improved blood flow in the penis by enhancing the function of certain important proteins while decreasing markers related to tissue damage. Notably, the treatment had a significant impact on the autophagy process—a way cells renew themselves—which is crucial for recovery in this scenario. Furthermore, vitamin D helped reduce apoptosis, or programmed cell death, which can complicate recovery after nerve injury.
Overall, our study indicates that vitamin D can be a vital ally in recovering erectile function following nerve damage, thanks to its ability to promote healing and reduce cell death within the affected tissues.
Read More
9
We explored the connection between vitamin D levels and erectile dysfunction (ED) in a study involving 58 patients struggling with ED and a control group of 26 healthy individuals. The research sought to understand if low vitamin D levels could worsen the severity of erectile dysfunction.
Among our findings, we discovered a strong correlation between vitamin D levels and ED severity, which was confirmed using the Sexual Health Inventory For Men (SHIM) questionnaire. Patients with lower vitamin D also experienced decreased testosterone levels, which suggests that vitamin D deficiency might contribute to both low testosterone and ED.
Interestingly, we observed that vitamin D levels had negative correlations with body mass index (BMI), cholesterol, and triglycerides, all of which can further impact erectile health. Additionally, we found a moderate correlation between the degree of ED severity and testosterone levels, emphasizing the interconnection of these factors.
This study highlights that a reduction in vitamin D, alongside lower testosterone and higher cholesterol, may play a significant role in the development and persistence of erectile dysfunction. Therefore, assessing vitamin D levels could serve as a useful marker for evaluating ED, indicating that measuring vitamin D should be a part of the diagnostic process for men facing erectile dysfunction.
Among our findings, we discovered a strong correlation between vitamin D levels and ED severity, which was confirmed using the Sexual Health Inventory For Men (SHIM) questionnaire. Patients with lower vitamin D also experienced decreased testosterone levels, which suggests that vitamin D deficiency might contribute to both low testosterone and ED.
Interestingly, we observed that vitamin D levels had negative correlations with body mass index (BMI), cholesterol, and triglycerides, all of which can further impact erectile health. Additionally, we found a moderate correlation between the degree of ED severity and testosterone levels, emphasizing the interconnection of these factors.
This study highlights that a reduction in vitamin D, alongside lower testosterone and higher cholesterol, may play a significant role in the development and persistence of erectile dysfunction. Therefore, assessing vitamin D levels could serve as a useful marker for evaluating ED, indicating that measuring vitamin D should be a part of the diagnostic process for men facing erectile dysfunction.
Read More
Most Useful Reviews
7.5
Vitamin D benefits
6 people found this helpful
Dee recommends this vitamin D supplement as I have limited sun exposure and struggle with vitamin D production. I've chosen the 5000IU dosage because excessive vitamin D may cause kidney dysfunction, which is a concern I take seriously.
Read More
9
Bone health impact
1 people found this helpful
I understand that vitamin D deficiency can lead to serious health issues such as osteomalacia in adults and rickets in children. As a fat-soluble vitamin, too much can cause problems like hypercalcemia. I appreciate vitamin D in foods like mushrooms and seafood.
Read More
7.5
Improved health
1 people found this helpful
I take two capsules of vitamin D twice daily after blood tests indicated a deficiency. Over time, I've started to feel better, particularly regarding my erectile dysfunction. I believe the quality of the product is good, and I would recommend it.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 16 Researches
6.5
- All Researches
9
We investigated the effects of vitamin D on erectile dysfunction specifically in the context of nerve injury. This research involved 18 male Sprague-Dawley rats, divided into groups for control, nerve injury, and treatment with vitamin D after nerve injury. By measuring changes in intracavernosal pressure, we could assess how well vitamin D helped restore erectile function in the rats with nerve damage.
Our findings revealed that vitamin D not only eased the negative effects of hypoxia and reduced fibrosis but also promoted the restoration of erectile function. We observed that vitamin D improved blood flow in the penis by enhancing the function of certain important proteins while decreasing markers related to tissue damage. Notably, the treatment had a significant impact on the autophagy process—a way cells renew themselves—which is crucial for recovery in this scenario. Furthermore, vitamin D helped reduce apoptosis, or programmed cell death, which can complicate recovery after nerve injury.
Overall, our study indicates that vitamin D can be a vital ally in recovering erectile function following nerve damage, thanks to its ability to promote healing and reduce cell death within the affected tissues.
Our findings revealed that vitamin D not only eased the negative effects of hypoxia and reduced fibrosis but also promoted the restoration of erectile function. We observed that vitamin D improved blood flow in the penis by enhancing the function of certain important proteins while decreasing markers related to tissue damage. Notably, the treatment had a significant impact on the autophagy process—a way cells renew themselves—which is crucial for recovery in this scenario. Furthermore, vitamin D helped reduce apoptosis, or programmed cell death, which can complicate recovery after nerve injury.
Overall, our study indicates that vitamin D can be a vital ally in recovering erectile function following nerve damage, thanks to its ability to promote healing and reduce cell death within the affected tissues.
Read More
9
Vitamin D may improve ED symptoms
We examined the potential benefits of vitamin D replacement for men experiencing erectile dysfunction (ED) and lower urinary tract symptoms (LUTS) who did not respond to everyday tadalafil treatment. Between September 2017 and August 2020, we focused on patients who had taken 5 mg of tadalafil daily for at least a month without success. For those with low vitamin D levels, we administered an oral vitamin D3 treatment of 100,000 IU weekly for one month.
After this month of treatment, we noticed significant improvements in both erectile function and urinary symptoms. Specifically, the scores from the International Index of Erectile Function (IIEF-EF) and the International Prostate Symptom Score showed marked enhancements post-treatment compared to their results before receiving vitamin D.
These findings suggest that assessing vitamin D levels and addressing deficiencies could play a crucial role in enhancing treatment outcomes for men struggling with ED, especially when traditional medications like PDE-5 inhibitors haven’t worked. It opens a promising avenue for further research into how vitamin D could aid in managing erectile dysfunction.
After this month of treatment, we noticed significant improvements in both erectile function and urinary symptoms. Specifically, the scores from the International Index of Erectile Function (IIEF-EF) and the International Prostate Symptom Score showed marked enhancements post-treatment compared to their results before receiving vitamin D.
These findings suggest that assessing vitamin D levels and addressing deficiencies could play a crucial role in enhancing treatment outcomes for men struggling with ED, especially when traditional medications like PDE-5 inhibitors haven’t worked. It opens a promising avenue for further research into how vitamin D could aid in managing erectile dysfunction.
Read More
9
We investigated the impact of vitamin D on erectile dysfunction (ED) in patients also dealing with vitamin D deficiency (VDD). By looking at a group of 111 men over a few years, we separated them into two groups. One group received daily tadalafil, a common ED medication, while the other group got both tadalafil and vitamin D supplements.
Our findings revealed that the men who received vitamin D alongside tadalafil showed significant improvements in various aspects of their sexual health, including erectile function and sexual desire. This was in contrast to the group that just took tadalafil without vitamin D, which did not exhibit any changes in vitamin D levels or comparable improvements.
This study suggests that adding vitamin D may enhance the effectiveness of tadalafil, helping men with ED who also suffer from vitamin D deficiency. Our conclusions propose that vitamin D could play a beneficial role in managing ED more effectively.
Our findings revealed that the men who received vitamin D alongside tadalafil showed significant improvements in various aspects of their sexual health, including erectile function and sexual desire. This was in contrast to the group that just took tadalafil without vitamin D, which did not exhibit any changes in vitamin D levels or comparable improvements.
This study suggests that adding vitamin D may enhance the effectiveness of tadalafil, helping men with ED who also suffer from vitamin D deficiency. Our conclusions propose that vitamin D could play a beneficial role in managing ED more effectively.
Read More
9
We explored the connection between vitamin D levels and erectile dysfunction (ED) in a study involving 58 patients struggling with ED and a control group of 26 healthy individuals. The research sought to understand if low vitamin D levels could worsen the severity of erectile dysfunction.
Among our findings, we discovered a strong correlation between vitamin D levels and ED severity, which was confirmed using the Sexual Health Inventory For Men (SHIM) questionnaire. Patients with lower vitamin D also experienced decreased testosterone levels, which suggests that vitamin D deficiency might contribute to both low testosterone and ED.
Interestingly, we observed that vitamin D levels had negative correlations with body mass index (BMI), cholesterol, and triglycerides, all of which can further impact erectile health. Additionally, we found a moderate correlation between the degree of ED severity and testosterone levels, emphasizing the interconnection of these factors.
This study highlights that a reduction in vitamin D, alongside lower testosterone and higher cholesterol, may play a significant role in the development and persistence of erectile dysfunction. Therefore, assessing vitamin D levels could serve as a useful marker for evaluating ED, indicating that measuring vitamin D should be a part of the diagnostic process for men facing erectile dysfunction.
Among our findings, we discovered a strong correlation between vitamin D levels and ED severity, which was confirmed using the Sexual Health Inventory For Men (SHIM) questionnaire. Patients with lower vitamin D also experienced decreased testosterone levels, which suggests that vitamin D deficiency might contribute to both low testosterone and ED.
Interestingly, we observed that vitamin D levels had negative correlations with body mass index (BMI), cholesterol, and triglycerides, all of which can further impact erectile health. Additionally, we found a moderate correlation between the degree of ED severity and testosterone levels, emphasizing the interconnection of these factors.
This study highlights that a reduction in vitamin D, alongside lower testosterone and higher cholesterol, may play a significant role in the development and persistence of erectile dysfunction. Therefore, assessing vitamin D levels could serve as a useful marker for evaluating ED, indicating that measuring vitamin D should be a part of the diagnostic process for men facing erectile dysfunction.
Read More
8
We set out to understand how vitamin D levels might influence erectile dysfunction (ED), specifically focusing on the arteriogenic type of ED. The study involved 150 men who had been diagnosed with ED and evaluated through a standard questionnaire and specific tests.
What we found was quite telling. Men suffering from organic ED had noticeably lower vitamin D levels compared to those with psychogenic ED. Specifically, the average vitamin D level in those with arteriogenic ED was significantly lower than in men with other types of ED.
We observed that higher levels of vitamin D correlated positively with better erectile function. In essence, we discovered a potential link where low vitamin D levels could serve as an independent risk factor for arteriogenic ED. Based on our findings, we recommend that men experiencing ED should have their vitamin D levels checked regularly, and for those with low levels, supplementation may be beneficial.
What we found was quite telling. Men suffering from organic ED had noticeably lower vitamin D levels compared to those with psychogenic ED. Specifically, the average vitamin D level in those with arteriogenic ED was significantly lower than in men with other types of ED.
We observed that higher levels of vitamin D correlated positively with better erectile function. In essence, we discovered a potential link where low vitamin D levels could serve as an independent risk factor for arteriogenic ED. Based on our findings, we recommend that men experiencing ED should have their vitamin D levels checked regularly, and for those with low levels, supplementation may be beneficial.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Vitamin D benefits
6 people found this helpful
Dee recommends this vitamin D supplement as I have limited sun exposure and struggle with vitamin D production. I've chosen the 5000IU dosage because excessive vitamin D may cause kidney dysfunction, which is a concern I take seriously.
Read More
9
Bone health impact
1 people found this helpful
I understand that vitamin D deficiency can lead to serious health issues such as osteomalacia in adults and rickets in children. As a fat-soluble vitamin, too much can cause problems like hypercalcemia. I appreciate vitamin D in foods like mushrooms and seafood.
Read More
7.5
Improved health
1 people found this helpful
I take two capsules of vitamin D twice daily after blood tests indicated a deficiency. Over time, I've started to feel better, particularly regarding my erectile dysfunction. I believe the quality of the product is good, and I would recommend it.
Read More
Frequently Asked Questions
7.5
Improved health
1 people found this helpful
I take two capsules of vitamin D twice daily after blood tests indicated a deficiency. Over time, I've started to feel better, particularly regarding my erectile dysfunction. I believe the quality of the product is good, and I would recommend it.
9
Bone health impact
1 people found this helpful
I understand that vitamin D deficiency can lead to serious health issues such as osteomalacia in adults and rickets in children. As a fat-soluble vitamin, too much can cause problems like hypercalcemia. I appreciate vitamin D in foods like mushrooms and seafood.
7.5
Vitamin D benefits
6 people found this helpful
Dee recommends this vitamin D supplement as I have limited sun exposure and struggle with vitamin D production. I've chosen the 5000IU dosage because excessive vitamin D may cause kidney dysfunction, which is a concern I take seriously.
1
Vitamin D supplementation ineffective
We explored the direct impact of vitamin D supplementation on erectile dysfunction among older men through the D-Health Trial, which followed nearly 11,530 participants aged 60 to 84. Participants were randomly assigned to receive either 60,000 IU of vitamin D monthly or a placebo over a period of up to five years.
After three years, we assessed erectile dysfunction and found that while vitamin D levels increased significantly in the treatment group, the prevalence of erectile dysfunction remained almost identical between both groups—58.8% in the vitamin D group compared to 59.0% in the placebo group. Importantly, our analyses showed no evidence that vitamin D supplementation made any difference in erectile dysfunction for any subgroup of older men evaluated.
In conclusion, our findings suggest that taking vitamin D supplements is unlikely to prevent or alleviate erectile dysfunction. This highlights the need for further exploration into effective treatments for this common condition among older men.
After three years, we assessed erectile dysfunction and found that while vitamin D levels increased significantly in the treatment group, the prevalence of erectile dysfunction remained almost identical between both groups—58.8% in the vitamin D group compared to 59.0% in the placebo group. Importantly, our analyses showed no evidence that vitamin D supplementation made any difference in erectile dysfunction for any subgroup of older men evaluated.
In conclusion, our findings suggest that taking vitamin D supplements is unlikely to prevent or alleviate erectile dysfunction. This highlights the need for further exploration into effective treatments for this common condition among older men.
9
Vitamin D may improve ED symptoms
We examined the potential benefits of vitamin D replacement for men experiencing erectile dysfunction (ED) and lower urinary tract symptoms (LUTS) who did not respond to everyday tadalafil treatment. Between September 2017 and August 2020, we focused on patients who had taken 5 mg of tadalafil daily for at least a month without success. For those with low vitamin D levels, we administered an oral vitamin D3 treatment of 100,000 IU weekly for one month.
After this month of treatment, we noticed significant improvements in both erectile function and urinary symptoms. Specifically, the scores from the International Index of Erectile Function (IIEF-EF) and the International Prostate Symptom Score showed marked enhancements post-treatment compared to their results before receiving vitamin D.
These findings suggest that assessing vitamin D levels and addressing deficiencies could play a crucial role in enhancing treatment outcomes for men struggling with ED, especially when traditional medications like PDE-5 inhibitors haven’t worked. It opens a promising avenue for further research into how vitamin D could aid in managing erectile dysfunction.
After this month of treatment, we noticed significant improvements in both erectile function and urinary symptoms. Specifically, the scores from the International Index of Erectile Function (IIEF-EF) and the International Prostate Symptom Score showed marked enhancements post-treatment compared to their results before receiving vitamin D.
These findings suggest that assessing vitamin D levels and addressing deficiencies could play a crucial role in enhancing treatment outcomes for men struggling with ED, especially when traditional medications like PDE-5 inhibitors haven’t worked. It opens a promising avenue for further research into how vitamin D could aid in managing erectile dysfunction.
9
We investigated the impact of vitamin D on erectile dysfunction (ED) in patients also dealing with vitamin D deficiency (VDD). By looking at a group of 111 men over a few years, we separated them into two groups. One group received daily tadalafil, a common ED medication, while the other group got both tadalafil and vitamin D supplements.
Our findings revealed that the men who received vitamin D alongside tadalafil showed significant improvements in various aspects of their sexual health, including erectile function and sexual desire. This was in contrast to the group that just took tadalafil without vitamin D, which did not exhibit any changes in vitamin D levels or comparable improvements.
This study suggests that adding vitamin D may enhance the effectiveness of tadalafil, helping men with ED who also suffer from vitamin D deficiency. Our conclusions propose that vitamin D could play a beneficial role in managing ED more effectively.
Our findings revealed that the men who received vitamin D alongside tadalafil showed significant improvements in various aspects of their sexual health, including erectile function and sexual desire. This was in contrast to the group that just took tadalafil without vitamin D, which did not exhibit any changes in vitamin D levels or comparable improvements.
This study suggests that adding vitamin D may enhance the effectiveness of tadalafil, helping men with ED who also suffer from vitamin D deficiency. Our conclusions propose that vitamin D could play a beneficial role in managing ED more effectively.
References
- Duarte Romero B, Waterhouse M, Baxter C, McLeod DSA, English DR, et al. The effect of three years of vitamin D supplementation on erectile dysfunction: Results from the randomized placebo-controlled D-Health Trial. Clin Nutr ESPEN. 2024;60:109. doi:10.1016/j.clnesp.2024.01.011
- Crafa A, Cannarella R, Barbagallo F, Leanza C, Palazzolo R, et al. Mechanisms Suggesting a Relationship between Vitamin D and Erectile Dysfunction: An Overview. Biomolecules. 2023;13. doi:10.3390/biom13060930
- Zhu S, Xiong Y, Yu B, Wang H, Zhang F, et al. Vitamin D3 improved erectile function recovery by regulating autophagy and apoptosis in a rat model of cavernous nerve injury. Int J Impot Res. 2024;36:430. doi:10.1038/s41443-023-00679-4
- Zhang JH, Li W, Wang CY, Zhang AN, Jia BZ, et al. Correlation analysis of carotid artery intima-media thickness, serum 25(OH)D and men with erectile dysfunction. Front Endocrinol (Lausanne). 2022;13:1027430. doi:10.3389/fendo.2022.1027430
- Wu X, Zhang Y, Zhang W, Liu G, Jiang H, et al. The relationship between serum 25-hydroxy vitamin D and arteriogenic erectile dysfunction. Andrologia. 2022;54:e14568. doi:10.1111/and.14568
- Ermec B, Culha MG, Kocak G, Canat L, Otunctemur A, et al. The effect of vitamin D replacement in patients with lower urinary tract complaint/erectile dysfunction resistant to Tadalafil 5 mg treatment: A pilot clinical study. Andrologia. 2022;54:e14473. doi:10.1111/and.14473
- Liu G, Wu X, Zhang Y, Zhang W, Jiang H, et al. Serum Vitamin D Level and Erectile Dysfunction in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. Urol Int. 2022;106:1025. doi:10.1159/000523691
- Arıman A, Merder E, Çulha MG, Ermeç B, Karakanlı MU, et al. Relation of glycated hemoglobin and vitamin D deficiency with erectile dysfunction in patients with type 2 diabetes mellitus. Andrologia. 2021;53:e14076. doi:10.1111/and.14076
- Demirci A, Çakan M, Topçuoğlu M. Whether Adding Vitamin D to Tadalafil 5 mg Treatment Is Useful in Patients with Erectile Dysfunction and Vitamin D Deficiency?. Urol Int. 2021;105:514. doi:10.1159/000514056
- Dumbraveanu I, Banov P, Arian I, Ceban E. The Correlations of Clinical and Biochemical Indices of Vitamin D with Erectile Dysfunction. J Med Life. 2020;13:144. doi:10.25122/jml-2020-0009
- Horsanalı MO, Eren H, Dil E, Caglayan A, Erdogan O, et al. Novel predictive risk factor of erectile dysfunction: Serum 25-hydroxy vitamin D. Andrologia. 2020;52:e13767. doi:10.1111/and.13767
- Crafa A, Cannarella R, Condorelli RA, La Vignera S, Calogero AE. Is There an Association Between Vitamin D Deficiency and Erectile Dysfunction? A Systematic Review and Meta-Analysis. Nutrients. 2020;12. doi:10.3390/nu12051411
- Wei Y, Chen P, Chen Q, Zhu H. Serum vitamin D levels and erectile dysfunction: A systematic review and meta-analysis. Andrologia. 2019;51:e13211. doi:10.1111/and.13211
- Krysiak R, Szwajkosz A, Okopień B. The effect of low vitamin D status on sexual functioning and depressive symptoms in apparently healthy men: a pilot study. Int J Impot Res. 2018;30:224. doi:10.1038/s41443-018-0041-7
- Culha MG, Atalay HA, Canat HL, Alkan I, Ozbir S, et al. The relationship between erectile dysfunction severity, mean platelet volume and vitamin D levels. Aging Male. 2020;23:173. doi:10.1080/13685538.2018.1459544
- Basat S, Sivritepe R, Ortaboz D, Sevim Çalık E, Küçük EV, et al. The relationship between vitamin D level and erectile dysfunction in patients with type 2 diabetes mellitus. Aging Male. 2018;21:111. doi:10.1080/13685538.2017.1379488
